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Antihistamine long term health effects, nothing to sneeze at!

Its allergy season, which has many of us reach for over-the-counter (OTC) antihistamines to alleviate the all-too-familiar symptoms of sneezing, itching, and congestion. While these medications can provide quick relief, it’s essential to consider the potential long-term effects on your health


Antihistamines work by blocking the action of histamine, a chemical released by the immune system during an allergic reaction. They can be classified into first-generation antihistamines (like diphenhydramine) and second-generation antihistamines (like loratadine). While both types effectively reduce allergy symptoms, they have different side effects and possible long-term implications.


Potential Long-Term Effects of OTC Antihistamines


1.  Cognitive Impairment: Some studies suggest that long-term use of first-generation antihistamines may be linked to cognitive decline and an increased risk of dementia. A study published in the Journal of the American Geriatrics Society found that older adults who used anticholinergic medications (which include many first-generation antihistamines) had a higher risk of developing dementia.


2. Dependency and Tolerance: Chronic use of antihistamines can lead to tolerance, where the effectiveness diminishes over time, prompting users to take higher doses. This can increase the risk of side effects and may lead to dependency on these medications for relief.


3. Anticholinergic Effects: Many first-generation antihistamines have anticholinergic properties, which can cause side effects such as dry mouth, blurred vision, constipation, and urinary retention. Long-term exposure to anticholinergic drugs has been linked to severe health issues, including increased risk of falls and fractures in older adults. 


4. Gut Health Disruption: Studies indicate that long-term antihistamine use may negatively impact gut microbiota, which is crucial for overall health and immune function. Gut health disruption can lead to a variety of issues, including digestive problems and increased susceptibility to allergies


6. Increased Risk of Respiratory Issues: Prolonged use of antihistamines can lead to a paradoxical worsening of allergy symptoms, as the body may become conditioned to the medication. This can increase nasal congestion and respiratory problems.


5. Interactions with Other Medications: Antihistamines can interact with various medications, possibly reducing their effectiveness or amplifying side effects.


Natural Alternatives for Allergy Relief


If you're seeking ways to manage your allergies without relying on long-term antihistamine use, consider these natural alternatives:


1. Herbal Remedies

Nettle (Urtica dioica): This herb is a natural antihistamine known for reducing inflammation. Studies have shown that nettle can help alleviate allergy symptoms, making it an excellent choice during allergy season. It can be consumed as a tea or taken in capsule form.

Eyebright (Euphrasia officinalis) is a powerful herb for relieving hay fever symptoms. Traditionally used to soothe irritated eyes and respiratory issues, it is a natural anti-inflammatory and antihistamine. 

Elderflower (Sambucus nigra) is a fantastic ally for managing seasonal allergies. Its anti-inflammatory and antihistamine properties help reduce symptoms like sneezing and congestion. Brew elderflower tea or use it in syrups to enjoy its benefits.

Garlic (Allium sativum) is a potent natural remedy for seasonal allergies. Its anti-inflammatory and immune-boosting properties help reduce histamine production, alleviating symptoms like sneezing and congestion. Incorporate fresh garlic into meals or take it in supplement form to harness its allergy-fighting benefits and support overall respiratory health! 

Quercetin: Found in foods like apples, onions, and citrus fruits, quercetin is a flavonoid with antihistamine properties. It helps stabilise mast cells and prevents the release of histamine, making it a great addition to your diet during allergy season.


⚠️ Herb Caution Alert! ⚠️

While herbs can offer many health benefits, it is crucial to consult a trained herbal healthcare professional before using them. Self-diagnosing and treating with herbs can lead to unwanted side effects, interactions with medications, or worsening health conditions. Always seek expert advice to ensure safe and effective use! 


2. Dietary Changes


Increase Antioxidant-Rich Foods: Eating a diet rich in fruits and vegetables high in vitamins C and E can help support your immune system and reduce inflammation. Berries, citrus fruits, and leafy greens are particularly beneficial.


Stay Hydrated: Drinking plenty of water helps moisten mucous membranes, reducing congestion and irritation. Aim for about 2 litres of fluids daily—water and herbal teas the best choices. 


Limit Processed Foods: Sugar, refined carbohydrates, and artificial additives can increase inflammation and worsen allergy symptoms. Focusing on whole, unprocessed foods can positively impact our health in many ways.


3. Lifestyle Modifications


Manage Stress: Stress can exacerbate allergy symptoms. Incorporating relaxation techniques like yoga, meditation, and deep-breathing exercises can help keep symptoms in check.


Improve Indoor Air Quality: Use air purifiers, keep windows closed during high pollen days, and regularly clean your living space to reduce allergens. Add some indoor plants to your decor to help keep your air clean - Just don’t forget to water them ;) 


Regular Exercise: Physical activity boosts your immune function and overall well-being. Just remember to shower and change clothes after being outside to wash away any pollen.


Get Enough Sleep: Quality sleep is crucial for a healthy immune system. Aim for 7-9 hours of sleep per night to allow your body to recover and regulate its functions effectively.



While over-the-counter antihistamines can provide temporary relief from allergy symptoms, their long-term use may pose risks to your health. Exploring natural alternatives such as herbs, dietary adjustments, and lifestyle changes can not only help manage your allergies but also promote overall well-being.


Before making significant changes to your health regimen, consult with a healthcare professional or a naturopath to tailor the best approach for your needs. With a little effort, you can enjoy a sneeze-free spring while supporting your long-term health!

Find out how naturopathy can help you get relief from your seasonal allergies. Book an appointment to discuss your health concerns. You can book your appointment here: https://fundamental-wellbeing.cliniko.com/bookings?business_id=38234&practitioner_id=56903&appointment_type_id=160392


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### References


Gray, S. L., et al. (2015). Anticholinergic use and cognitive function in older adults. Journal of the American Geriatrics Society.


Zito, J. M., et al. (2000). Trends in the prescribing of psychotropic medications to children. Archives of Pediatric and Adolescent Medicine.


Hanlon, J. T., et al. (2001). Medication use and cognitive function in older adults. Archives of Internal Medicine.


Pizzorno, J., & Murray, M. T. (2013). Textbook of Natural Medicine. Elsevier.

Vena, G. A., et al. (2014). Efficacy of nettle extract in the treatment of allergic rhinitis. Phytotherapy Research.


Orsini, J. A. (2019). Antihistamine use and its effects on oral health. Journal of Dental Hygiene.


Sgambato, A., et al. (2015). Gut microbiota: A role in the pathophysiology of respiratory diseases. Frontiers in Microbiology.


Andrade, C., et al. (2003). Interactions of antihistamines with other drugs. Indian Journal of Psychiatry.


Vena, G. A., et al. (2014). Efficacy of nettle extract in the treatment of allergic rhinitis. Phytotherapy Research.


Sweeney, C. R. (2017). The impact of quercetin on allergic symptoms. Journal of Nutrition.


Houghton, P. J. (1996). The role of antioxidant-rich foods in health. Journal of Medicinal Food.


Michalak, J., et al. (2018). The role of stress in allergy. Journal of Allergy and Clinical Immunology.


Walker, A. B., et al. (2017). Sleep duration and quality in relation to immune function. Sleep Health.


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Mudgee & the Mid-Western Region

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info@fundamentalwellbeing.com.au

 

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